GENOTOXICITY AND CYTOTOXICITY EVALUATION OF THE NEOLIGNAN ANALOGUE 2-(4-NITROPHENOXY)-1PHENYLETHANONE AND ITS PROTECTIVE EFFECT AGAINST DNA DAMAGE.

Genotoxicity and Cytotoxicity Evaluation of the Neolignan Analogue 2-(4-Nitrophenoxy)-1Phenylethanone and its Protective Effect Against DNA Damage.

Neolignans are secondary metabolites found in various groups of Angiosperms.They belong to a class of natural compounds with great diversity of chemical structures and pharmacological activities.These compounds are formed by linking two phenylpropanoid units.Several compounds that have ability to prevent genetic damage have been isolated from plant

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The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation

Abstract Background Cells have evolved quality control mechanisms to ensure protein homeostasis by detecting and degrading aberrant mRNAs and proteins.A common source of aberrant mRNAs is premature Penis Pumps and Enlargers polyadenylation, which can result in non-functional protein products.Translating ribosomes that encounter poly(A) sequences ar

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